Condition: Melanoma · Sponsor: Shenzhen Geno-Immune Medical Institute
The purpose of this study is to assess the feasibility, safety and efficacy of combination immunotherapy based on CAR T cells, cytotoxic T lymphocytes (CTLs), and dendritic cell (DC) vaccines modified with GM-CSF and B7-2 (CD86) against melanoma, which targets CAR T specific surface antigens such as GD2, CTL specific antigens such as MAGE-A4, gp100 and a pool of melanoma specific antigens presented by the DCs. Another goal of the study is to learn more about the function and persistence of the CAR T cells and antigen-specific immune effectors in patients.
This description comes directly from the study's public registry record.
Lung-Ji Chang, PhD · +86-13671121909 · c@szgimi.org
Always discuss trial participation with your own doctor first.
| Shenzhen Geno-Immune Medical Institute | Shenzhen, Guangdong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06739226