Study identifier: NCT06739148 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

The Enhancement Effect of Low-Level Laser Therapy for Muscle Training with Combined NMES and BFR

Condition: Blood Flow Restriction Therapy · Neuromuscular Electrical Stimulation (NMES) · Laser Therapy, Low-Level  ·  Sponsor: National Cheng-Kung University Hospital

PhaseNA
Planned participants44
Who can joinAll sexes, 20 Years to 40 Years
Healthy volunteersYes

About this study

Blood flow restriction training (BFR) with neuromuscular stimulation (NMES) is employed for individuals with limited mobility and joint issues. However, this approach is highly susceptible to muscle fatigue, despite its potential beneficial effects on muscle strength. Recently, there has been growing interest in using low-level laser therapy (LLLT) to address muscle fatigue. LLLT, known for improving microcirculation and mitochondrial function, shows promise in alleviating enhanced muscle fatigue associated with combined BFR and NMES training. Despite these positive effects, there is limited knowledge about the short-term training impact of combined BFR and NMES with LLLT preconditioning. This project aims to investigate whether the photobiomodulation effects of LLLT could further enhance the training benefits of combined BFR and NMES. The study will employ an integrated analysis of decomposition surface EMG, EEG, and mechanomyogram to explore the behavior and neuromuscular mechanisms underlying the training benefits. If additional benefits are identified, LLLT pre-conditioning is recommended to enhance the use of combined BFR and NMES.

This description comes directly from the study's public registry record.

Talk to the study team

Ing-Shiou Hwang, PhD  ·  +886 62353535  ·  ensureh@gmail.com

Pei-Fen Li, Master  ·  +886 62353535  ·  abbylee52034@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

National Chen Kong University Hospital, TainanTainan, TaiwanRecruiting

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