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Study identifier: NCT06680596 Synced from ClinicalTrials.gov · August 04, 2026
● Enrolling By Invitation

Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd Therapy

Condition: Breast Cancer Metastatic · Breast Cancer Stage IV  ·  Sponsor: UNICANCER

PhasePhase 2
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

After an initial screening phase to identify patients with persistent blood circulating DNA tumors, patients will be enrolled in the treatment phase that was designed as an open-label, multicentre, phase II study, to test the efficacy of trastuzumab deruxtecan in terms of progression-free survival (PFS).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (38)

Chu Amiens PicardieAmiens, France
Clinique de L'Europe Amiens - CtheAmiens, France
Centre Hospitalier D'AuxerreAuxerre, France
Sainte Catherine Institut Du Cancer Avignon ProvenceAvignon, France
Centre Hospitalier de la Côte BasqueBayonne, France
Centre Hospitalier de BeauvaisBeauvais, France
Hôpital Simone Veil de BloisBlois, France
Centre Hospitalier de Boulogne-Sur-MerBoulogne-sur-Mer, France
Chu de Brest - Hôpital Cavale BlancheBrest, France
Clinique Pasteur Lanroze - Cfro - Groupe Vivalto SanteBrest, France
Centre Hospitalier William MoreyChalon-sur-Saône, France
Centre Hospitalier de CholetCholet, France

+ 26 more locations — full list on the registry record.

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