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Study identifier: NCT06635824 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)

Condition: PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC  ·  Sponsor: Genmab

PhasePhase 3
Planned participants191
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, randomized, open-label, international, Phase 3 trial to evaluate the efficacy and safety of acasunlimab in combination with pembrolizumab versus docetaxel (standard of care) in participants with locally advanced (unresectable stage IIIB/C) or programmed death ligand 1 (PD-L1)-positive metastatic non-small cell lung cancer (NSCLC) who have been treated with programmed cell death protein 1 (PD-1)/PD-L1 inhibitor and platinum-containing chemotherapy, administered either in combination or sequentially in the locally advanced (unresectable stage IIIB/C) or metastatic setting.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (247)

Arizona Blood and Cancer SpecialistsTucson, Arizona, United States
Usc Norris Comprehensive Cancer CenterLos Angeles, California, United States
Kaiser Permanente Vallejo Medical CenterVallejo, California, United States
Ocala Oncology Center P.L.Ocala, Florida, United States
Orlando Regional Medical CenterOrlando, Florida, United States
University Cancer & Blood Center, LLCAthens, Georgia, United States
Piedmont Cancer Institute AtlantaAtlanta, Georgia, United States
Piedmont Cancer Institute - Sandy Springs (Atlanta) OfficeAtlanta, Georgia, United States
Piedmont Cancer Institute - Fayetteville OfficeFayetteville, Georgia, United States
Piedmont Cancer Institute - Newnan OfficeNewnan, Georgia, United States
Piedmont Cancer Institute - Stockbridge OfficeStockbridge, Georgia, United States
Kaiser Foundation HospitalsHonolulu, Hawaii, United States

+ 235 more locations — full list on the registry record.

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