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Study identifier: NCT06635135 Synced from ClinicalTrials.gov · August 05, 2026
● Terminated

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

Condition: Depressive Disorder, Major · Anhedonia  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants47
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess how well aticaprant works compared to placebo when given in addition to antidepressant therapy (selective serotonin reuptake inhibitor \[SSRI\] or serotonin-norepinephrine reuptake inhibitor \[SNRI\]) in preventing return of depression symptoms in participants with major depressive disorder who experience a loss of interest and pleasure and who achieve a stable response after treatment with adjunctive aticaprant.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (95)

Preferred Research PartnersLittle Rock, Arkansas, United States
Wake Research PRI EncinoEncino, California, United States
Wr Pri LlcNewport Beach, California, United States
ATP Clinical ResearchOrange, California, United States
Myndful ResearchRedlands, California, United States
Artemis Institute for Clinical ResearchSan Diego, California, United States
UHC ResearchDoral, Florida, United States
Pharmax Research Clinic IncMiami, Florida, United States
GTL Medical and Research GroupMiami, Florida, United States
International Research Associates, LLCMiami, Florida, United States
Harmony Clinical Research IncNorth Miami Beach, Florida, United States
APG Research LLCOrlando, Florida, United States

+ 83 more locations — full list on the registry record.

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