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Study identifier: NCT06631092 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast Cancer

Condition: Triple Negative Breast Cancer  ·  Sponsor: NEC Bio B.V

PhasePhase 1/Phase 2
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Phase I/II, multicenter, open-label, single-arm trial in triple-negative breast cancer patients under first-line neoadjuvant therapy with approved standard of care anti-PD-1 monoclonal antibody (PD-1 inhibitor), epirubicin/cyclophosphamide chemotherapy, and nab-paclitaxel therapy (cohort 1) or SoC carboplatin/paclitaxel and epirubicin/cyclophosphamide or doxorubicin/cyclophosphamide chemotherapy (cohort 2). NECVAX-NEO1 treatment in addition to standard of care anti-PD1 monoclonal antibody therapy can be prolonged after breast cancer surgery for another 24 weeks, according to the investigator's decision taking into consideration the study patient's health status.

This description comes directly from the study's public registry record.

Talk to the study team

Heinz Lubenau, Dr  ·  0049 621 950499  ·  info@nec-bio.com

Always discuss trial participation with your own doctor first.

Locations (2)

University Clinic ErlangenErlangen, GermanyRecruiting
National Center for Tumor Diseases HeidelbergHeidelberg, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06631092