Condition: Plaque Psoriasis · Sponsor: Alumis Inc
The goal of this clinical trial is to learn if ESK-001 works to treat moderate to severe plaque psoriasis. The main questions it aims to answer are: * Does ESK-001 reduce the severity of people's psoriasis? * How safe is ESK-001 in people with moderate to severe plaque psoriasis? The study includes 2 comparators: a placebo control (a 'dummy' tablet that does not contain the medicine ESK-001 but looks just like it) and an active control (apremilast, which is a medicine approved to treat psoriasis). People taking part in this study must be men or women aged at least 18 years and have had plaque psoriasis for at least 6 months, currently moderate to severe. Participants will: * take drug every day for 24 weeks. * visit the clinic for checkups and tests. * fill out questionnaires about their psoriasis, itch severity, and change in quality of life. * be assessed for health issues and side effects, physical examinations, vital signs, heart electrical activity measurements, and psychological health. * provide blood and urine samples.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
| Total Skin and Beauty Dermatology Center, PC | Birmingham, Alabama, United States | — |
| Chandler Clinical Trials | Chandler, Arizona, United States | — |
| Noble Clinical Research | Tucson, Arizona, United States | — |
| Zenith Research Inc. | Beverly Hills, California, United States | — |
| Raoof MD | Encino, California, United States | — |
| Long Beach Research Institute | Long Beach, California, United States | — |
| Dermatology Research Associates | Los Angeles, California, United States | — |
| Empire Clinical Research - Pomona | Pomona, California, United States | — |
| Integrative Skin Science and Research | Sacramento, California, United States | — |
| UC San Diego | San Diego, California, United States | — |
| Southern California Clinical Research | Santa Ana, California, United States | — |
| Clinical Science Institute Dermatology Institute | Santa Monica, California, United States | — |
+ 112 more locations — full list on the registry record.
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