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Study identifier: NCT06553027 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

Condition: Parkinson Disease  ·  Sponsor: Cerevance

PhasePhase 3
Planned participants330
Who can joinAll sexes, 30 Years to no upper limit
Healthy volunteersNo

About this study

This is a randomized, double-blind, placebo-controlled, multicenter study in participants with Parkinson's disease (PD) with motor fluctuations. Participants will be randomized to receive once-daily oral doses of either 75 milligrams (mg) CVN424 or 150 mg CVN424, or a matching placebo for 12 weeks. Participants who successfully complete this study and retain eligibility/suitability will be invited to participate in a future open-label extension (OLE) study.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (94)

The Kirklin Clinic of UAB HospitalBirmingham, Alabama, United States
University of Alabama at BirminghamBirmingham, Alabama, United States
University of Alabama at Birmingham ALS ClinicBirmingham, Alabama, United States
Barrow Neurological InstitutePhoenix, Arizona, United States
Muhammad Ali Parkinson CenterPhoenix, Arizona, United States
St. Joseph's Hospital and Medical CenterPhoenix, Arizona, United States
Parkinson's Research Centers of America - Orange countyAliso Viejo, California, United States
Parkinson's Research Centers of America - Orange CountyNewport Beach, California, United States
Parkinson's Research Centers of America - Palo AltoPalo Alto, California, United States
CenExel Rocky Mountain Clinical ResearchEnglewood, Colorado, United States
David and Rhoda Chase Family Movement Disorders Center - VernonVernon, Connecticut, United States
Parkinson's Disease and Movement Disorders Center of Boca RatonBoca Raton, Florida, United States

+ 82 more locations — full list on the registry record.

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