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Study identifier: NCT06532032 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With Metastatic Non-small Cell Lung Cancer

Condition: Carcinoma, Non-Small-Cell Lung  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 1/Phase 2
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to identify the recommended Phase 2 (combination) dose (RP2CD) of the amivantamab and docetaxel combination therapy in participants with metastatic non-small cell lung cancer (NSCLC) in Phase 1 (combination dose selection); and to evaluate the antitumor effect of the combination at the selected RP2CD in participants with NSCLC without oncogenic driver mutations with disease progression on platinum-based chemotherapy and immune checkpoint inhibitor, in the Phase 2 (expansion).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (15)

UCI Health Irvine HospitalIrvine, California, United States
Cancer and Blood Specialty ClinicLos Alamitos, California, United States
University of California Irvine Medical Center Chao Family Comprehensive Cancer CenterOrange, California, United States
Oncology Hematology AssociatesSpringfield, Missouri, United States
Hunterdon Hematology OncologyFlemington, New Jersey, United States
Virginia Cancer SpecialistsFairfax, Virginia, United States
Changhua Christian HospitalChanghua, Taiwan
Kaohsiung Medical University HospitalKaohsiung City, Taiwan
Chi Mei Medical Center Liu YingLiou Ying Township, Taiwan
Taichung Veterans General HospitalTaichung, Taiwan
National Taiwan University HospitalTaipei, Taiwan
Taipei Medical UniversityTaipei, Taiwan

+ 3 more locations — full list on the registry record.

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