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Study identifier: NCT06455449 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

Condition: Polymyositis, Dermatomyositis  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants240
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this multicenter, randomized, placebo-controlled and double-blind study is to evaluate the efficacy and safety of subcutaneous anifrolumab compared with placebo on the overall disease activity in participants with moderate to severe Idiopathic Inflammatory Myopathies (IIM) \[polymyositis (PM) or dermatomyositis (DM)\] while receiving standard of care (SoC) treatment.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (236)

Research SitePhoenix, Arizona, United StatesNot Yet Recruiting
Research SiteIrvine, California, United StatesRecruiting
Research SiteAurora, Colorado, United StatesRecruiting
Research SiteDenver, Colorado, United StatesNot Yet Recruiting
Research SiteNew Haven, Connecticut, United StatesRecruiting
Research SiteWashington D.C., District of Columbia, United StatesWithdrawn
Research SiteBoca Raton, Florida, United StatesRecruiting
Research SiteBoynton Beach, Florida, United StatesWithdrawn
Research SiteGainesville, Florida, United StatesWithdrawn
Research SiteMargate, Florida, United StatesSuspended
Research SiteMiami, Florida, United StatesWithdrawn
Research SiteMiami, Florida, United StatesRecruiting

+ 224 more locations — full list on the registry record.

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