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Study identifier: NCT06408935 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Condition: Crohn's Disease  ·  Sponsor: Janssen-Cilag Ltd.

PhasePhase 3
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy of guselkumab in healing of all layers of the digestive tract (transmural healing) with the help of a score called Magnetic Resonance Index of Activity (MaRIA) based on a scan at Week 48.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (84)

Center for Colitis and Crohns Disease University of CaliforniaSan Francisco, California, United States
The University of Chicago Medical Center (UCMC)Chicago, Illinois, United States
Washington University School Of MedicineSt Louis, Missouri, United States
Medical University of South CarolinaCharleston, South Carolina, United States
The Queen Elizabeth HospitalAdelaide, Australia
Concord Repatriation General HospitalConcord, Australia
Northern HospitalMelbourne, Australia
Fiona Stanley HospitalMurdoch, Australia
Mater Hospital BrisbaneSouth Brisbane, Australia
AZ Maria MiddelaresGhent, Belgium
CHU de LiegeLiège, Belgium
VitazSint-Niklaas, Belgium

+ 72 more locations — full list on the registry record.

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