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Study identifier: NCT06402331 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Condition: Metastatic Castration-resistant Prostate Cancer  ·  Sponsor: Fusion Pharmaceuticals Inc.

PhasePhase 2
Planned participants110
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, randomized, multicenter study of FPI-2265 (225Ac-PSMA-I\&T). Patient population is adult participants with PSMA positive mCRPC who have had previous treatment with with 177Lu-PSMA-617 or another 177Lu-PSMA radioconjugate (RC). The purpose of the study is to determine the safety and tolerability, and recommended dose and regiment of FPI-2265.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (18)

City of Hope Comprehensive Cancer CenterDuarte, California, United States
Hoag Health Center IrvineIrvine, California, United States
VA Greater Los Angeles Healthcare SystemLos Angeles, California, United States
University of California Los AngelesLos Angeles, California, United States
UCSF School of MedicineSan Francisco, California, United States
Biogenix Molecular, LLCMiami, Florida, United States
University of Iowa Hospitals and ClinicsIowa City, Iowa, United States
United TheranosticsGlen Burnie, Maryland, United States
BAMF HealthGrand Rapids, Michigan, United States
SSM Health Saint Louis University HospitalSt Louis, Missouri, United States
XCancerOmaha, Nebraska, United States
New Mexico Oncology Hematology Consultants Ltd.Albuquerque, New Mexico, United States

+ 6 more locations — full list on the registry record.

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