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Study identifier: NCT06367738 Synced from ClinicalTrials.gov · July 30, 2026
● Recruiting

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

Condition: Aging  ·  Sponsor: University of California, Berkeley

PhasePhase 1
Planned participants40
Who can joinAll sexes, 60 Years to 85 Years
Healthy volunteersYes

About this study

Participants in this study will undergo a series of non-invasive tests and activities designed to understand how a single dose of psilocybin might influence cognition and emotional well-being in healthy older adults. After providing written informed consent, eligible participants, aged between 60 and 85, will be randomly assigned to receive a dose of psilocybin ranging from a microdose to a moderate-to-high dose. Anatomical magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) will be used to assess changes in brain structure, while functional magnetic resonance imaging (fMRI) will be used to quantify changes in functional brain activity.

This description comes directly from the study's public registry record.

Talk to the study team

BCSP Research Staff  ·  (669) 244-2436  ·  bcspresearchsubjects@berkeley.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, BerkeleyBerkeley, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06367738