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Study identifier: NCT06340711 Synced from ClinicalTrials.gov · August 04, 2026
● Recruiting

Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

Condition: Esophageal Adenocarcinoma · Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma  ·  Sponsor: Weill Medical College of Cornell University

PhasePhase 2
Planned participants27
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to learn about of the research study drug, telomelysin (OBP-301), in combination with pembrolizumab in advanced or metastatic gastric or gastroesophageal junction (GEJ) cancer. The main question it aims to answer is whether this combination is safe and effective in this type of cancer. Participants will receive 5 injections of OBP-301, approximately every 2 weeks. OBP-301 will be injected directly into the tumor during an esophagogastroduodenoscopy (EGD). At the same time as the injection, a tumor biopsy will be taken. Participants will also receive pembrolizumab infusions every 6 weeks until disease progression or for a maximum of two years. Pembrolizumab infusions will occur on different days than OBP-301 injections.

This description comes directly from the study's public registry record.

Talk to the study team

Casey Owens  ·  646-962-6046  ·  cdo4001@med.cornell.edu

Myriam Elizaire-Williams  ·  mye4001@med.cornell.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Weill Cornell Medicine/NewYork-Presbyterian HospitalNew York, New York, United StatesRecruiting
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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