Condition: High Grade Glioma · Diffuse Intrinsic Pontine Glioma · Anaplastic Astrocytoma · Sponsor: Nationwide Children's Hospital
The goal of this study is to determine the response of the study drug loratinib in treating children who are newly diagnosed high-grade glioma with a fusion in ALK or ROS1. It will also evaluate the safety of lorlatinib when given with chemotherapy or after radiation therapy.
This description comes directly from the study's public registry record.
Kelsey H Troyer, PhD · 16147223284 · kelsey.troyer@nationwidechildrens.org
Always discuss trial participation with your own doctor first.
| Children's Hospital Colorado | Aurora, Colorado, United States | Not Yet Recruiting |
| Children's National Medical Center | Washington D.C., District of Columbia, United States | Not Yet Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago, Illinois, United States | Not Yet Recruiting |
| Dana-Farber Cancer Institute | Boston, Massachusetts, United States | Not Yet Recruiting |
| Duke University Health System | Durham, North Carolina, United States | Not Yet Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati, Ohio, United States | Recruiting |
| Nationwide Children's Hospital | Columbus, Ohio, United States | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia, Pennsylvania, United States | Not Yet Recruiting |
| Texas Children's Hospital | Houston, Texas, United States | Not Yet Recruiting |
| Seattle Children's Hospital | Seattle, Washington, United States | Not Yet Recruiting |
| Sydney Children's Hospital | Randwick, New South Wales, Australia | Not Yet Recruiting |
| Queensland Children's Hospital | South Brisbane, Queensland, Australia | Not Yet Recruiting |
+ 6 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06333899