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Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change
Condition: Overweight · Obesity · Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
About this study
Background: In a previous study, participants were lived at the NIH and randomly received either a low-fat or a low-carbohydrate diet for 2 weeks and then switched to the other diet for 2 more weeks. Participants who received the low-carbohydrate diet first lost more body fat at the end of the study than those who received the low-fat diet first. Researchers want to see if they can repeat that result in a longer weight loss study when participants live at home. Objective: To test the effects of diet order in people receiving either a low-fat or low-carbohydrate diet first for 4 weeks and then immediately switched to the other diet for another 4 weeks. Eligibility: Adults aged 19 to 50 years with a body mass index of 25 or more. Design: Participants will complete the study at their homes, but there will be 3 required visits to the NIH. Participants will drink a special type of water 2 weeks before the baseline NIH visit and collect urine samples at home to measure how many calories they burn. Before the diets begin, participants will visit the NIH for baseline testing when they will have a metabolism test while relaxing in a bed with a plastic hood over their head to collect the air they breathe out. They will have scans to measure their bone density and how much muscle and body fat they have. They will give stool, blood, and urine samples. Participants will be asked to eat a specific diet for 4 weeks followed by a different diet for 4 weeks. All meals will be delivere…
This description comes directly from the study's public registry record.
Talk to the study team
Nan Zhai, C.R.N.P. · (301) 827-3324 · nan.zhai@nih.gov
Valerie L Darcey · (301) 402-9689 · valerie.darcey@nih.gov
Always discuss trial participation with your own doctor first.
Locations (1)
| National Institutes of Health Clinical Center | Bethesda, Maryland, United States | Recruiting |
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