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Study identifier: NCT06292013 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Condition: Atherosclerotic Cardiovascular Disease (ASCVD) · Elevated Lp(a)  ·  Sponsor: Eli Lilly and Company

PhasePhase 3
Planned participants17300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart attack or stroke. The study drug will be administered subcutaneously (SC) (under the skin). Approximately 1700 additional participants will be enrolled in an addendum to explore Lp(a) lowering with an alternative dosing schema.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (931)

Birmingham Clinical ResearchBirmingham, Alabama, United States
Alliance for Multispecialty Research, LLCDaphne, Alabama, United States
SEC Clinical ResearchDothan, Alabama, United States
Alliance for Multispecialty Research, LLCMobile, Alabama, United States
Mobile Heart SpecialistsMobile, Alabama, United States
Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLCGilbert, Arizona, United States
Mercy Gilbert Medical CenterGilbert, Arizona, United States
Sun City Clinical ResearchGlendale, Arizona, United States
Elite Clinical Studies, LLCPhoenix, Arizona, United States
Helios Clinical Research - PhoenixPhoenix, Arizona, United States
Absolute Clinical ResearchPhoenix, Arizona, United States
Clinical Research Institute of Arizona (CRI) - Sun City WestSun City West, Arizona, United States

+ 919 more locations — full list on the registry record.

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