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Study identifier: NCT06252649 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Amgen

PhasePhase 3
Planned participants450
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to compare progression free survival (PFS) in treatment-naïve participants with KRAS p.G12C mutated metastatic colorectal cancer (mCRC) receiving sotorasib, panitumumab and FOLFIRI vs FOLFIRI with or without bevacizumab-awwb.

This description comes directly from the study's public registry record.

Talk to the study team

Amgen Call Center  ·  866-572-6436  ·  medinfo@amgen.com

Always discuss trial participation with your own doctor first.

Locations (291)

Ironwood Cancer and Research Centers ScottsdaleChandler, Arizona, United StatesRecruiting
Providence Saint Jude Medical CenterFullerton, California, United StatesTerminated
City of Hope National Medical CenterLong Beach, California, United StatesRecruiting
Cancer and Blood Research Center, LLCLos Alamitos, California, United StatesRecruiting
California Research InstituteLos Angeles, California, United StatesRecruiting
Norwalk HospitalNorwalk, Connecticut, United StatesTerminated
Cancer Specialists of North Florida - SouthpointJacksonville, Florida, United StatesRecruiting
D and H Cancer Research CenterMargate, Florida, United StatesTerminated
Mid Florida Hematology and Oncology Centers PAOrange City, Florida, United StatesTerminated
Boca Raton Clinical Research Medical Center IncPlantation, Florida, United StatesTerminated
Georgia Cancer SpecialistsAtlanta, Georgia, United StatesTerminated
Insight Research InstituteChicago, Illinois, United StatesRecruiting

+ 279 more locations — full list on the registry record.

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