Condition: Solid Malignant Tumors · Sponsor: Bayer
Regorafenib is an anti-cancer drug that blocks several proteins which are involved in the growth of cancer. It has been approved for different types of cancers of the digestive system and is being tested for use in some other solid tumors. Cancers that start in an organ, a muscle, or a bone form a solid tumor. This study is for participants with solid tumors who have been taking regorafenib in other Bayer studies. They can continue taking regorafenib if it is working when treatment with regorafenib in their previous study ends. The main purpose of this study is to find: * How safe is the continued treatment with regorafenib in participants with solid tumors? * How well is the continued treatment with regorafenib tolerated by participants with solid tumors? Participants will continue with the same dose of regorafenib that they were taking in their previous study as long as the treatment works for them/they want to continue the treatment/other medical conditions do not prevent them from participating in the study. For participants that are under 18 years of age, regorafenib tablets will be taken by mouth once daily for 2 weeks and repeat again after a 1-week gap. For participants that are over 18 years of age, regorafenib tablets will be taken by mouth once daily for 3 weeks and repeat again after a 1-week gap. At the start of the study, researchers will review participants' records from the previous study. During the study, researchers will use blood samples and X-rays ta…
This description comes directly from the study's public registry record.
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| CHU Lille - Hopital Claude Huriez - Service Gastro-entrologie adulte | Lille, France | — |
| Hôpital Beaujon - Clichy | Clichy, Île-de-France Region, France | — |
| Hôpital Paul Brousse - Villejuif | Villejuif, Île-de-France Region, France | — |
| Saitama Cancer Center | Kitaadachi, Saitama, Japan | — |
| Seoul National University Hospital | Oncology | Seoul, South Korea | — |
| Hospital Infantil Universitario Nino Jesus | Oncologia Pediatrica | Madrid, Spain | — |
| China Medical University Hospital | Taichung, Taiwan | — |
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