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A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis
Condition: Thrombolysis · Symptomatic Proximal Deep Vein Thrombosis · Sponsor: Bayer
About this study
Researchers are looking for a better way to treat people who have deep vein thrombosis (DVT). DVT is a condition that occurs when a blood clot forms in a deep vein in the leg. DVT is called 'proximal' when the clot is formed in the veins of the hip, thigh, and knee. DVT can cause serious health problems. The blood clots in the veins can break loose and can then travel through the bloodstream and get stuck in the lungs, blocking blood flow to the lungs. Symptoms of DVT include swelling, pain, and tenderness in the affected leg, as well as redness and warmth in the area. Currently, DVT is usually treated using blood thinners to prevent the clot from getting bigger or breaking off and traveling to the lungs. However, blood thinners may not be able to remove a blood clot quickly and may not be suitable for everyone who has DVT. BAY3018250 is a drug that works by dissolving blood clots. In this study, researchers will compare BAY3018250 with placebo to learn how well it works and how safe it is in participants with proximal DVT. A placebo looks like the study drug but does not have any medicine in it. Using a placebo helps researchers to confirm that the results observed during the study were caused by the study drug and not by other factors. The main purposes of this study are to learn: * How well BAY3018250 works in dissolving blood clots in participants with proximal DVT and * How safe is BAY3018250 as a treatment for participants with proximal DVT? For this, the researche…
This description comes directly from the study's public registry record.
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Locations (68)
| Universiteit Ziekenhuis Antwerpen | Thoraxheelkunde Afdeling | Antwerp, Belgium | — |
| Imelda - Vascular Surgery Dept | Bonheiden, Belgium | — |
| Ziekenhuis Oost-Limburg | Genk, Sint-Jan campus - Thoracic Vascular Surgery Department | Genk, Belgium | — |
| UZ Gent | Ghent, Belgium | — |
| AZ Groeninge - Campus Kennedylaan | Kortrijk, Belgium | — |
| Katholieke Universiteit Leuven (KU Leuven) - Center for Molecular and Vascular Biology (CMVB) | Leuven, Belgium | — |
| AZ Sint-Maarten | Mechelen, Belgium | — |
| University Multiprofile Hospital For Active Treatment Kanev AD | Rousse, Bulgaria | — |
| Specialized Hospital For Active Cardiology Treatment Medica Kor EAD | Rousse, Bulgaria | — |
| University Multiprofile Hospital For Active Treatment 'Alexandrovska' EAD | Sofia, Bulgaria | — |
| University Multiprofile Hospital for Active Treatment 'Sveta Ekaterina' EAD, Sofia | Sofia, Bulgaria | — |
| Medical Institute Ministry of Interior | Sofia, Bulgaria | — |
+ 56 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06149520