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Study identifier: NCT06123988 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer

Condition: HER2-positive Breast Cancer · Advanced Breast Cancer  ·  Sponsor: University of Miami

PhaseNA
Planned participants260
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to test if four different programs (prolonged overnighting fasting alone, exercise alone, a combination of prolonged overnight fasting and exercise, or general health education sessions alone) can reduce fatigue in women with advanced or metastatic breast cancer who are receiving a medication called a cyclin-dependent kinases-4 and 6 (CDK4/6) inhibitor (e.g., palbociclib, ribociclib, or abemaciclib), with or without HER2-directed therapy (e.g., trastuzumab ± pertuzumab), or in combination with both a CDK4/6 inhibitor and a PI3K inhibitor, within the past 90 days.

This description comes directly from the study's public registry record.

Talk to the study team

Grey Freylersythe, BS  ·  (305) 243-9832  ·  g.freylersythe@med.miami.edu

Tracy E Crane, PhD, RDN  ·  (305) 243-8255  ·  tecrane@med.miami.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Arizona State UniversityPhoenix, Arizona, United StatesNot Yet Recruiting
University of MiamiMiami, Florida, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06123988