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Study identifier: NCT06107673 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dalpiciclib Plus AI (Neoadjuvant Endocrine Therapy) Compared With Neoadjuvant Chemotherapy in Early Breast Cancer (EBC)

Condition: Breast Cancer  ·  Sponsor: Hebei Medical University Fourth Hospital

PhasePhase 2
Planned participants144
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a multi-center, randomized, prospective phase II clinical trial aimed at exploring and evaluating the efficacy of dalpiciclib combined with AI in neoadjuvant treatment for ER strong positive(ER≥50%),HER2-negative, Ki-67≤20%,T1-3N1M0 postmenopausal breast cancer. The primary objectives are to demonstrate non-inferiority in efficacy compared to chemotherapy and to assess its superior safety profile.

This description comes directly from the study's public registry record.

Talk to the study team

lina zhang  ·  15830981676  ·  linazh_001@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Fourth Hospital of Hebei Medical UniversityShijiazhuang, Hebei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06107673