Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation
Condition: Metastatic Colorectal Cancer · CRC · KRAS/NRAS Mutation · Sponsor: Cardiff Oncology
About this study
The purpose of this study is to assess 2 different doses of onvansertib to select the lowest dose that is maximally effective, and to assess the safety, efficacy, pharmacokinetics, and pharmacodynamics of onvansertib in combination with FOLFIRI + bevacizumab or FOLFOX + bevacizumab in patients with KRAS or NRAS-mutated metastatic colorectal cancer (CRC) in the first-line setting.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (41)
| Mayo Clinic - Arizona | Phoenix, Arizona, United States | — |
| The University of Arizona Cancer Center | Tucson, Arizona, United States | — |
| St. Bernards Medical Center | Jonesboro, Arkansas, United States | — |
| Highlands Oncology Group | Springdale, Arkansas, United States | — |
| Pacific Cancer Medical Center | Anaheim, California, United States | — |
| Comprehensive Blood and Cancer Center - Bakersfield | Bakersfield, California, United States | — |
| Orange Coast Memorial Medical Center | Fountain Valley, California, United States | — |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | — |
| Norris Comprehensive Cancer Center | Los Angeles, California, United States | — |
| UCLA Department of Medicine-Hematology/Oncology | Los Angeles, California, United States | — |
| Sharp Memorial Hospital | San Diego, California, United States | — |
| Torrance Memorial Physician Network - Cancer Care and Infusion Center | Torrance, California, United States | — |
+ 29 more locations — full list on the registry record.
Follow this study
Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.
We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06106308