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Study identifier: NCT06097975 Synced from ClinicalTrials.gov · July 30, 2026
● Recruiting

A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma

Condition: Recurrent Glioblastoma  ·  Sponsor: Universitair Ziekenhuis Brussel

PhasePhase 1
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this phase I interventional study is to determine the safety and feasibility of the proposed investigational (neo-)adjuvant treatment regimen in patients with resectable reccurent glioblastoma. Participants will: * receive neo-adjuvant administration of intravenous immunotherapy * followed by a maximal safe neurosurgical resection * afterwards, immunotherapy will be injected into the brain tissue * followed by insertion of an Ommaya reservoir * postoperatively, administration of immunotherapy will be continued

This description comes directly from the study's public registry record.

Talk to the study team

Bart Neyns, MD, PhD  ·  003224776415  ·  datamanagement.oncologie@uzbrussel.be

Always discuss trial participation with your own doctor first.

Locations (1)

UZ BrusselBrussels, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT06097975