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Study identifier: NCT06052332 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer

Condition: Locally Advanced Rectal Cancer · Older People  ·  Sponsor: Jules Bordet Institute

PhaseNA
Planned participants230
Who can joinAll sexes, 70 Years to no upper limit
Healthy volunteersNo

About this study

The SHAPERS study is a multicentre, open-label, randomised, pragmatic clinical trial, comparing standard-of-care neoadjuvant treatment options for older (i.e., ≥70 years) subjects with high-risk stage II and stage III rectal cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Sophie Lepannetier, phD  ·  +32 (0)2 541 34 56  ·  ctsu.shapers@hubruxelles.be

Ikram El Idrissi  ·  +32 (0)2 541 30 81  ·  ctsu.shapers@hubruxelles.be

Always discuss trial participation with your own doctor first.

Locations (19)

ZAS AntwerpenAntwerp, Antwerpen, BelgiumRecruiting
UZA AntwerpenEdegem, Antwerpen, BelgiumRecruiting
AZ TurnhoutTurnhout, Antwerpen, BelgiumRecruiting
Institut Jules BordetAnderlecht, Brussels Capital, BelgiumRecruiting
Chirec DeltaAuderghem, Brussels Capital, BelgiumRecruiting
CHU Saint-PierreBrussels, Brussels Capital, BelgiumRecruiting
CHU BrugmannBrussels, Brussels Capital, BelgiumRecruiting
UZ GentGhent, East Flanders, BelgiumRecruiting
AZ NikolaasSint-Niklaas, East Flanders, BelgiumRecruiting
Hôpital de JolimontHaine-Saint-Paul, Hainaut, BelgiumRecruiting
EpicuraHornu, Hainaut, BelgiumRecruiting
CHU Ambroise PareMons, Hainaut, BelgiumNot Yet Recruiting

+ 7 more locations — full list on the registry record.

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