Study identifier: NCT06036862 Synced from ClinicalTrials.gov · August 05, 2026
● Study status: Recruiting

Utilization of Transanal Endoscopy in the Treatment of Anastomotic Stenosis

Condition: Anastomotic Stenosis  ·  Sponsor: Sun Yat-sen University

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Severe rectal anastomotic stenosis can not only cause intestinal obstruction, but also be accompanied by frequent defecation, which affects the quality of life, and patients face the outcome of permanent stoma or temporary stoma again. Traditional transabdominal resection and reconstruction of rectal anastomotic stenosis is more likely to occur due to unclear anatomical structure, dense scars around the intestinal canal, complications such as ureteral and urethral injury and massive presacral hemorrhage. In addition,41%of patients with anastomotic stenosis who underwent reoperation through abdominal surgery had anastomotic leakage again, and up to 30% of patients could not close the stoma. The advantages of transanal total mesorectal excision (taTME) using a transanal approach for total mesorectal excision in the treatment of middle and low rectal cancer with difficult pelvis have been demonstrated by our group. However, taTME has rarely been explored in the treatment of anastomotic stenosis. Our team retrospectively summarized the patients who underwent transabdominal transanal endoscopic resection and reconstruction of anastomotic stenosis (l-taTME), and initially demonstrated the safety and effectiveness of this surgical method, with a stoma closure rate of 90%. Although the advantages of l-taTME in the treatment of severe rectal anastomotic stenosis are obvious in theory and preliminary clinical practice, there is a lack of prospective studies. Therefore, the investigator…

This description comes directly from the study's public registry record.

Talk to the study team

Liang Huang, Doctor  ·  15989101216  ·  huangl75@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sixth Affiliated Hospital of Sun yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting

Follow this study

Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.

We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →