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Study identifier: NCT06031441 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Condition: Locally Advanced Solid Tumors · Recurrent Solid Tumors · Metastatic Solid Tumors  ·  Sponsor: Genentech, Inc.

PhasePhase 1
Planned participants65
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human Phase I, open-label, dose-escalation and expansion study designed to evaluate the safety, tolerability, pharmacokinetics, immunogenicity, pharmacodynamic, and preliminary anti-tumor activity of RO7566802 as a single agent and in combination with atezolizumab in participants with locally advanced, recurrent, or metastatic incurable solid tumor malignancies. Participants will be enrolled in 2 stages: dose escalation and expansion.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (18)

University of Alabama at Birmingham (UAB)Birmingham, Alabama, United States
Yale Cancer CenterNew Haven, Connecticut, United States
Icahn School of Medicine at Mount Sinai (ISMMS)New York, New York, United States
The Ohio State UniversityColumbus, Ohio, United States
Magee-Woman's HospitalHarrisburg, Pennsylvania, United States
SCRI Oncology PartnersNashville, Tennessee, United States
St Vincent's Hospital SydneyDarlinghurst, New South Wales, Australia
Peter Maccallum Cancer CentreMelbourne, Victoria, Australia
British Columbia Cancer Agency - 600 10th Ave WVancouver, British Columbia, Canada
Princess Margaret Cancer CentreToronto, Ontario, Canada
National University HospitalSingapore, Singapore
National Cancer CentreSingapore, Singapore

+ 6 more locations — full list on the registry record.

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