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Study identifier: NCT06003231 Synced from ClinicalTrials.gov · August 05, 2026
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A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Condition: Carcinoma, Non-Small-Cell Lung · Ovarian Neoplasms · Endometrial Neoplasms  ·  Sponsor: Seagen, a wholly owned subsidiary of Pfizer

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial is studying advanced or metastatic solid tumors. Once a solid tumor has grown very large in one spot or has spread to other places in the body, it is called advanced or metastatic cancer. Participants in this study must have head and neck cancer, non-small cell lung cancer, endometrial cancer, or ovarian cancer. In the first part of the study, participants must have tumors that have a marker called HER2. This clinical trial uses an experimental drug called disitamab vedotin (DV). DV is a type of antibody-drug conjugate or ADC. ADCs are designed to stick to cancer cells and kill them. In this study, all participants will get DV once every 2 weeks. This study is being done to see if DV works to treat different types of solid tumors that express HER2. It will also test how safe the drug is for participants. This trial will also study what side effects happen when participants get the drug. A side effect is anything a drug does to your body besides treating the disease.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (96)

Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersChandler, Arizona, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersGilbert, Arizona, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersGlendale, Arizona, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersMesa, Arizona, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersMesa, Arizona, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersPhoenix, Arizona, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research CentersScottsdale, Arizona, United States
Valkyrie Clinical Trials(Additional Suite)Los Angeles, California, United States
Valkyrie Clinical TrialsLos Angeles, California, United States
University of California Davis Comprehenvise Cancer CenterSacramento, California, United States
University of California Davis Medical CenterSacramento, California, United States
Providence Medical FoundationSanta Rosa, California, United States

+ 84 more locations — full list on the registry record.

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