Study identifier: NCT05990738 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy

Condition: Small Cell Lung Carcinoma (SCLC)  ·  Sponsor: Boehringer Ingelheim

PhasePhase 1
Planned participants69
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is open to adults with extensive stage small cell lung cancer. The study is in people with advanced cancer that had previously received platinum-based chemotherapy and are eligible to receive a single agent chemotherapy treatment. The purpose of this study is to find the highest dose of BI 764532 that people can tolerate when taken together with a single agent chemotherapy. BI 764532 is an antibody-like molecule that may help the immune system fight cancer. Participants may continue to take BI 764532 as long as they benefit from treatment and can tolerate it. During this time, participants visit the study site regularly. The visits also depend on the response to the treatment. At the study visits, the doctors check the health of the participants, take necessary laboratory tests, and note any health problems that could have been caused by the study treatment.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (14)

MedStar Georgetown University HospitalWashington D.C., District of Columbia, United States
Mayo Clinic - FloridaJacksonville, Florida, United States
University of MiamiMiami, Florida, United States
Virginia Commonwealth UniversityRichmond, Virginia, United States
INS CurieParis, France
HOP CivilStrasbourg, France
Institut Gustave RoussyVillejuif, France
Universitätsklinikum Carl Gustav Carus DresdenDresden, Germany
Universitätsklinikum ErlangenErlangen, Germany
Thoraxklinik-Heidelberg gGmbH am Universitätsklinikum HeidelbergHeidelberg, Germany
Universitätsmedizin der Johannes Gutenberg-Universität MainzMainz, Germany
Universitätsklinikum Würzburg AÖRWürzburg, Germany

+ 2 more locations — full list on the registry record.

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