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Study identifier: NCT05978063 Synced from ClinicalTrials.gov · August 04, 2026
● Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Condition: Pruritus · Notalgia Paresthetica  ·  Sponsor: Cara Therapeutics, Inc.

PhasePhase 2/Phase 3
Planned participants214
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a 2-part, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of twice-daily (BID) oral difelikefalin for moderate-to-severe pruritus in adult subjects with NP.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (58)

Cara Therapeutics Study SiteBirmingham, Alabama, United States
Cara Therapeutics Study SitePhoenix, Arizona, United States
Cara Therapeutics Study SiteFayetteville, Arkansas, United States
Cara Therapeutics Study SiteHot Springs, Arkansas, United States
Cara Therapeutics Study SiteEncino, California, United States
Cara Therapeutics Study SiteFountain Valley, California, United States
Cara Therapeutics Study SiteLos Angeles, California, United States
Cara Therapeutics Study SiteNorthridge, California, United States
Cara Therapeutics Study SiteValencia, California, United States
Cara Therapeutics Study SiteCoral Gables, Florida, United States
Cara Therapeutics Study SiteHollywood, Florida, United States
Cara Therapeutics Study SiteLutz, Florida, United States

+ 46 more locations — full list on the registry record.

Sponsor or site team? See the site landscape for this trial — listed sites, countries, and recruiting-density context.

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