Condition: Brain Tumor, Primary · Sponsor: IRCCS San Raffaele
Gliomas are the most frequent type of primary brain tumors in adults; among them glioblastoma multiforme (GBM) is the most malignant, being associated with the worst prognosis. Glutamate (Glu) is an aminoacid, responsible for essential functions in the Central Nervous System (CNS), acting both as metabolite and neurotransmitter. It is essential for regulating cellular metabolism and developmental synaptogenesis, cellular migration, differentiation and death. Recent scientific evidences have demonstrated alteration in Glu synthesis and signaling being directly involved in GBM growth and invasion
This description comes directly from the study's public registry record.
Sincinelli Laura · 0226436658 · sincinelli.laura@hsr.it
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| IRCCS San Raffaele Scientific Institute | Milan, Milan, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05775458