Condition: Subjects Treated With Busulfan · Sponsor: Saladax Biomedical, Inc.
Busulfan (Busulfex®) is an alkylating drug used as a conditioning regimen prior to allogeneic hematopoietic stem cell transplantation. Busulfan has wide inter- and intra-patient pharmacokinetic variability resulting in variable exposure leading to increased risk of toxicities or sub-optimal treatment outcomes. Therapeutic drug monitoring of busulfan using patient plasma samples would benefit clinicians by providing the ability to personalize the dose to achieve a target busulfan exposure.
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| Robert H. Lurie Comprehensive Cancer Center of Northwestern University | Chicago, Illinois, United States | Active Not Recruiting |
| Rutgers Cancer Institute | New Brunswick, New Jersey, United States | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston, Texas, United States | Active Not Recruiting |
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