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Study identifier: NCT05664464 Synced from ClinicalTrials.gov · July 30, 2026
● Recruiting

Glutamate Inhibitors in Glioblastoma

Condition: Glioblastoma  ·  Sponsor: University of Zurich

PhasePhase 1/Phase 2
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this 1:1 randomized, multi-center, open-label phase Ib/II clinical trial is to explore the efficacy of the add-on of the anti-glutamatergic drugs gabapentin, sulfasalazine and memantine to standard chemoradiotherapy with temozolomide compared to chemoradiotherapy alone in patients with newly diagnosed glioblastoma.

This description comes directly from the study's public registry record.

Talk to the study team

Hans-Georg Wirsching, MD  ·  +41432532928  ·  hans-georg.wirsching@usz.ch

Michael Weller, MD  ·  +41442555513  ·  michael.weller@usz.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital ZurichZurich, Canton of Zurich, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT05664464