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Study identifier: NCT05637801 Synced from ClinicalTrials.gov · August 04, 2026
● Active Not Recruiting

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study)

Condition: Alzheimer Disease · Alzheimer Disease 1 · Alzheimer Disease 2  ·  Sponsor: Cognito Therapeutics, Inc.

PhaseNA
Planned participants670
Who can joinAll sexes, 50 Years to 90 Years
Healthy volunteersNo

About this study

This is a randomized, double-blind, sham-controlled pivotal study of sensory stimulation in subjects with mild to moderate AD. Up to approximately 670 subjects will be treated with either Active or Sham investigational device, Spectris™ AD, for 60 minutes daily for approximately 12 months. Efficacy will be measured using the Integrated Alzheimer's Disease Mini-Mental State Exam (MMSE) Activities of Daily Living (ADCS-ADL) Rating Scale (iADMARS).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (68)

CCT Research - Gilbert Neurology PartnersGilbert, Arizona, United States
Barrow Neurological InstitutePhoenix, Arizona, United States
CCT Research - Foothills Research CenterPhoenix, Arizona, United States
Banner Sun Health Research InstituteSun City, Arizona, United States
Advanced Research Center, IncAnaheim, California, United States
ATP Clinical Research, Inc.Costa Mesa, California, United States
Neurology Center of North Orange CountyFullerton, California, United States
Syrentis Clinical ResearchSanta Ana, California, United States
Office of Elizabeth Zarate-Rowell, MDSeal Beach, California, United States
Mile High Research CenterDenver, Colorado, United States
JEM Research InstituteAtlantis, Florida, United States
Visionary Investigators Network- AventuraAventura, Florida, United States

+ 56 more locations — full list on the registry record.

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