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Study identifier: NCT05636176 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

Condition: Heart Failure  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants4899
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get ziltivekimab or placebo. Participants will get study medicine for once-monthly injections either in a pre-filled syringe to inject the study medicine into a skinfold or a pen-injector to inject the study medicine into flat skin. The study is expected to last for up to 4 years. Participants will have up to 20 clinic visits. Participants will have to use a study app on their phone to record and share information about all their injections of study medicine and to fill in questionnaires.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (1013)

Advanced Cardiovascular, LLCAlexander City, Alabama, United States
Eastern Shore Rsrch Inst, LLCFairhope, Alabama, United States
Heart Center Rsrch_HunstvilleHuntsville, Alabama, United States
Banner University Medical CtrPhoenix, Arizona, United States
Cardiology & Medicine ClinicLittle Rock, Arkansas, United States
InvivoCure -2Alhambra, California, United States
National Heart Institute CalBeverly Hills, California, United States
Valley Clinical TrialsCovina, California, United States
Scripps Memorial Hospital La JollaLa Jolla, California, United States
Purushotham & Akther Kotha MD, inc.La Mesa, California, United States
VA Loma Linda Hlthcr SysLoma Linda, California, United States
Biopharma Clinical Research Services, LLCLos Angeles, California, United States

+ 1001 more locations — full list on the registry record.

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