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Study identifier: NCT05609370 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study Investigating the Efficacy and Safety of Alcestobart (LBL-007) Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Condition: Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer  ·  Sponsor: BeiGene

PhasePhase 1/Phase 2
Planned participants113
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1b/2 study to investigate the efficacy and safety of alcestobart (LBL-007) plus tislelizumab when administered in combination with bevacizumab plus fluoropyrimidine, and alcestobart in combination with bevacizumab plus fluoropyrimidine versus bevacizumab plus fluoropyrimidine to participants with colorectal cancer.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (64)

Alaska Oncology and Hematology, LlcAnchorage, Alaska, United States
Banner Md Anderson Cancer CenterGilbert, Arizona, United States
Helios Clinical ResearchCerritos, California, United States
Valkyrie Clinical TrialsLos Angeles, California, United States
Usc Norris Comprehensive Cancer Center (Nccc)Los Angeles, California, United States
UCLA HematologyoncologyLos Angeles, California, United States
Hoag Memorial PresbyterianNewport Beach, California, United States
Kaiser Permanente Northern CaliforniaVallejo, California, United States
Baptist Md Anderson Cancer CenterJacksonville, Florida, United States
Fort Wayne Medical Oncology and HematologyFort Wayne, Indiana, United States
Baptist Health LexingtonLexington, Kentucky, United States
University of Kentucky Markey Cancer CenterLexington, Kentucky, United States

+ 52 more locations — full list on the registry record.

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