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Study identifier: NCT05609097 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction

Condition: Heart Failure With Reduced Ejection Fraction  ·  Sponsor: University of Virginia

PhaseNA
Planned participants92
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

This study is trying to find out whether performing a hybrid aerobic-resistance exercise training program (titled PRIME: Peripheral Remodeling via Intermittent Muscular Exercise) results in better health outcomes than the traditional exercise training program (called COMBO) that is used in individuals with heart failure with reduced ejection fraction (HFrEF). Participants will be randomized (like the flip of a coin) to either PRIME (investigational) or the traditional exercise program (standard of care).

This description comes directly from the study's public registry record.

Talk to the study team

Ben Stephenson  ·  434-243-8677  ·  bls4qq@virginia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Virginia, Department of KinesiologyCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05609097