A Study of ZEN003694 in People With Squamous Cell Lung Cancer
Condition: Squamous Cell Lung Cancer · Sponsor: Memorial Sloan Kettering Cancer Center
About this study
The purpose of this study is to find out whether ZEN003694 is an effective treatment for people with advanced squamous cell lung cancer with a mutation in the NSD3 gene. ZEN003694 is a type of drug called a BET inhibitor. Researchers think ZEN003694 may help here because the drug works by blocking a group of proteins called bromodomain and extra-terminal (BET) proteins, which may counteract the effect of NSD3 on tumor growth. Blocking these proteins may slow or stop the growth of the cancer.
This description comes directly from the study's public registry record.
Talk to the study team
Paul Paik, MD · 646-608-3759 · paikp@mskcc.org
Mark Kris, MD · 646-608-3914
Always discuss trial participation with your own doctor first.
Locations (7)
| Memorial Sloan Kettering at Basking Ridge Limited Protocol Activities | Basking Ridge, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Monmouth (All Protocol Activities) | Middletown, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Bergen (All Protocol Activities) | Montvale, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities ) | Commack, New York, United States | Recruiting |
| Memorial Sloan Kettering Westchester (All Protocol Activities) | Harrison, New York, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | New York, New York, United States | Recruiting |
| Memorial Sloan Kettering Nassau (All Protocol Activities) | Uniondale, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05607108