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Study identifier: NCT05591222 Synced from ClinicalTrials.gov · August 04, 2026
● Terminated

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

Condition: Discoid Lupus Erythematosus  ·  Sponsor: Amgen

PhasePhase 2
Planned participants72
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

A Phase 2, double-blind, randomized, placebo-controlled parallel-group study to evaluate the efficacy and safety of daxdilimab in participants with moderate-to-severe active primary Discoid Lupus Erythematosus (DLE) refractory to standard of care.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (68)

Arkansas Research TrialsNorth Little Rock, Arkansas, United States
Wallace Medical GroupBeverly Hills, California, United States
The Center for Dermatology Clinical ResearchFremont, California, United States
Clinical Science InstituteSanta Monica, California, United States
Miami Dermatology & Laser ResearchMiami, Florida, United States
Dawes Fretzin Clinical Research Group, LLCIndianapolis, Indiana, United States
Detroit Clinical Research Center, PCFarmington Hills, Michigan, United States
Michigan Dermatology InstituteWaterford, Michigan, United States
Minnesota Clinical Study CenterNew Brighton, Minnesota, United States
MediSearch Clinical TrialsSaint Joseph, Missouri, United States
Forest Hills DermatologyForest Hills, New York, United States
Ohio State UniversityColumbus, Ohio, United States

+ 56 more locations — full list on the registry record.

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