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Study identifier: NCT05567796 Synced from ClinicalTrials.gov · August 05, 2026
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A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight

Condition: Obesity  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants3400
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This study has 2 parts: First part is the main study and second part is the extension study. During the main study participants will receive 1 of 4 study medicines. If participants continue in the extension study, they will not receive any study medicine during the extension. The main study will look at how well CagriSema helps participants with excess body weight lose weight compared to a "dummy" medicine and 2 other medicines, cagrilintide and semaglutide. Participants will either get CagriSema, cagrilintide,semaglutide or "dummy" medicine. Which treatment participants get is decided by chance. They will take one injection once a week. The study medicine is injected briefly with a thin needle, typically in the stomach, thighs or upper arms. Extension study: After the main study, not all participants will continue in the extension study. The study staff will tell the participant if they will continue or not into the extension study. In the extension study we will look at what happens to the participant's body weight and diseases related to excess body weight after the participant stops taking the study medicine. The main study will last for about 1½ years and the extension study will last for another 2 years.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (256)

Univ of Alabama BirminghamBirmingham, Alabama, United States
Velocity Clin Res Los AngelesLos Angeles, California, United States
Velocity Clin Res WstlkeLos Angeles, California, United States
Univ of Colorado at DenverAurora, Colorado, United States
OptumCare Clinical Trials LLCGolden, Colorado, United States
Northeast Research InstituteFleming Island, Florida, United States
South Broward Research LLCMiramar, Florida, United States
Clinical Neuroscience SolutionOrlando, Florida, United States
Florida Inst For Clin ResOrlando, Florida, United States
Florida Institute for Clinical researchOrlando, Florida, United States
Clinical Trial Res Assoc,IncPlantation, Florida, United States
Hope Clin Res & WellnessConyers, Georgia, United States

+ 244 more locations — full list on the registry record.

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