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Study identifier: NCT05557695 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom

Condition: Chronic Lymphocytic Leukemia, CLL  ·  Sponsor: AstraZeneca

PhaseN/A
Planned participants350
Who can joinAll sexes, 18 Years to 130 Years
Healthy volunteersNo

About this study

This is a retrospective observational research study to describe the characteristics and real-world clinical outcomes of patients with chronic lymphocytic leukaemia receiving acalabrutinib in the United Kingdom (the EPIC study). Physicians treating chronic lymphocytic leukaemia patients with acalabrutinib, where the patients started treatment as part of the acalabrutinib Early Access Programme (EAP), will be invited to recruit patients. Clinical data will be extracted from the patients' clinical records in line with local laws. Data from this study will provide UK-specific real-world data on patients who were started on acalabrutinib as part of the UK acalabrutinib EAP.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (29)

Research SiteAylesbury, United KingdomRecruiting
Research SiteBath, United KingdomRecruiting
Research SiteBirmingham, United KingdomRecruiting
Research SiteBournemouth, United KingdomRecruiting
Research SiteCardiff, United KingdomRecruiting
Research SiteCornwall, United KingdomRecruiting
Research SiteDartford, United KingdomRecruiting
Research SiteDerby, United KingdomRecruiting
Research SiteDoncaster, United KingdomRecruiting
Research SiteDorset, United KingdomRecruiting
Research SiteEastbourne, United KingdomRecruiting
Research SiteHull, United KingdomRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05557695