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Study identifier: NCT05523167 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

Condition: Active Idiopathic Inflammatory Myopathy · Myositis · Dermatomyositis  ·  Sponsor: argenx

PhasePhase 2/Phase 3
Planned participants265
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study's purpose is to measure the treatment response from efgartigimod PH20 SC compared with placebo in participants with Idiopathic Inflammatory Myopathy (IIM). Participants with the IIM subtypes of dermatomyositis (DM), immune-mediated necrotizing myopathy (IMNM), or certain other subtypes of polymyositis (PM; including antisynthetase syndrome \[ASyS\]) will be included in the study. Treatment response will be measured by Total improvement score (TIS).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (202)

Neuromuscular Research CenterPhoenix, Arizona, United States
HonorHealth Neurology - Bob Bove Neuroscience Institute - NeurologyScottsdale, Arizona, United States
Attune Health Research, IncBeverly Hills, California, United States
University of Southern California Norris Comprehensive Cancer CenterLos Angeles, California, United States
Profound Research LLC - OceansideOceanside, California, United States
University of California, IrvineOrange, California, United States
Eisenhower Medical CenterRancho Mirage, California, United States
Stanford Medicine Outpatient Center - Stanford Dermatology Clinic-Stanford University School of MedicineRedwood City, California, United States
California Pacific Medical Center - Sutter HealthSan Francisco, California, United States
Amyotrophic Lateral Sclerosis (ALS) Treatment Center,University of California San Francisco (UCSF)San Francisco, California, United States
Denver Arthritis ClinicDenver, Colorado, United States
Yale Cancer Center-Yale University School Of MedicineNew Haven, Connecticut, United States

+ 190 more locations — full list on the registry record.

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