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Study identifier: NCT05490446 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Condition: Myelodysplastic Syndromes  ·  Sponsor: Agios Pharmaceuticals, Inc.

PhasePhase 2
Planned participants87
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This purpose of this study is to establish proof of concept of tebapivat in participants with LR-MDS in Phase 2a and to evaluate the effect of tebapivat on transfusion independence (TI) in participants with LR-MDS in phase 2b.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (45)

Innovative Clinical Research Institute WhittierLakewood, California, United States
David Geffen School of Medicine at UCLALos Angeles, California, United States
Emad Ibrahim, MD, Inc.Redlands, California, United States
Smilow Cancer Hospital at Yale New HavenNew Haven, Connecticut, United States
Mayo Clinic Jacksonville - PPDSJacksonville, Florida, United States
Edward H. Kaplan MD & AssociatesSkokie, Illinois, United States
Washington University School of MedicineSt Louis, Missouri, United States
Memorial Sloan Kettering Cancer CenterLong Island City, New York, United States
Duke Adult Blood and Marrow ClinicDurham, North Carolina, United States
Monash Health, Monash Medical CentreClayton, Victoria, Australia
Ordensklinikum Linz GmbH ElisabethinenLinz, Upper Austria, Austria
Fakultni nemocnice OstravaOstrava, Czechia

+ 33 more locations — full list on the registry record.

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