Condition: Carcinoma, Hepatocellular · Cirrhosis · Sponsor: VA Office of Research and Development
The study is a randomized trial of two different screening methods for early detection of liver cancer in patients with cirrhosis of the liver. The goal of PREMIUM is to compare an abbreviated version of the diagnostic gold standard for HCC (aMRI) +AFP to the standard-of-care screening (US+AFP) in patients at high risk of developing HCC. The investigators hypothesize that HCC will be detected at earlier stages, allowing for more curative treatments and resulting in a reduction in HCC-related mortality.
This description comes directly from the study's public registry record.
George N Ioannou, MD MS · (206) 277-3136 · George.Ioannou@va.gov
Always discuss trial participation with your own doctor first.
| Birmingham VA Medical Center, Birmingham, AL | Birmingham, Alabama, United States | Recruiting |
| Southern Arizona VA Health Care System, Tucson, AZ | Tucson, Arizona, United States | Recruiting |
| Central Arkansas Veterans Healthcare System , Little Rock, AR | Little Rock, Arkansas, United States | Recruiting |
| VA Long Beach Healthcare System, Long Beach, CA | Long Beach, California, United States | Recruiting |
| VA Palo Alto Health Care System, Palo Alto, CA | Palo Alto, California, United States | Recruiting |
| VA Northern California Health Care System, Mather, CA | Sacramento, California, United States | Recruiting |
| VA San Diego Healthcare System, San Diego, CA | San Diego, California, United States | Recruiting |
| VA Greater Los Angeles Healthcare System, West Los Angeles, CA | West Los Angeles, California, United States | Recruiting |
| Rocky Mountain Regional VA Medical Center, Aurora, CO | Aurora, Colorado, United States | Recruiting |
| VA Connecticut Healthcare System West Haven Campus, West Haven, CT | West Haven, Connecticut, United States | Recruiting |
| Washington DC VA Medical Center, Washington, DC | Washington D.C., District of Columbia, United States | Recruiting |
| Miami VA Healthcare System, Miami, FL | Miami, Florida, United States | Recruiting |
+ 22 more locations — full list on the registry record.
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