EichorEICHOR
Study identifier: NCT05444257 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Condition: Cystic Fibrosis  ·  Sponsor: Vertex Pharmaceuticals Incorporated

PhasePhase 3
Planned participants822
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the long-term safety, tolerability, and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in participants with cystic fibrosis.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (195)

University of Alabama at BirminghamBirmingham, Alabama, United States
Banner University of Arizona Medical CenterTucson, Arizona, United States
University of Arkansas for Medical SciencesLittle Rock, Arkansas, United States
Miller Children's Hospital / Long Beach MemorialLong Beach, California, United States
Children's Hospital Los AngelesLos Angeles, California, United States
Kaiser PermanenteOakland, California, United States
University of California Davis Medical CenterSacramento, California, United States
University of California San Francisco, Lung Transplant ProgramSan Francisco, California, United States
Children's Hospital of ColoradoAurora, Colorado, United States
National Jewish HealthDenver, Colorado, United States
University of Florida, Shands HospitalGainesville, Florida, United States
Joe DiMaggio Cystic Fibrosis & Pulmonary CenterHollywood, Florida, United States

+ 183 more locations — full list on the registry record.

Follow this study

Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.

We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →