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Study identifier: NCT05431088 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 2/3 Study in Adult and Adolescent Participants With SCD

Condition: Sickle Cell Disease  ·  Sponsor: Pfizer

PhasePhase 2/Phase 3
Planned participants389
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of osivelotor.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (49)

Smilow Cancer HospitalNew Haven, Connecticut, United StatesNot Yet Recruiting
Edward Jenner Research Group Center LLCPlantation, Florida, United StatesRecruiting
Pediatric Hematology / Oncology a division of Kidz Medical servicesWest Palm Beach, Florida, United StatesNot Yet Recruiting
St. Mary's Medical CenterWest Palm Beach, Florida, United StatesNot Yet Recruiting
Alpha Clinical Research GeorgiaDunwoody, Georgia, United StatesActive Not Recruiting
Sonar Clinical ResearchRiverdale, Georgia, United StatesActive Not Recruiting
University of Illinois at Chicago Clinical Research CenterChicago, Illinois, United StatesNot Yet Recruiting
University of Illinois Hospital and Health Sciences System - Investigational Drug Services (IDS)Chicago, Illinois, United StatesNot Yet Recruiting
University of Illinois Hospital and Health Sciences SystemChicago, Illinois, United StatesNot Yet Recruiting
LSU Health Baton Rouge-North ClinicBaton Rouge, Louisiana, United StatesActive Not Recruiting
Our Lady of the Lake Hospital, Inc.Baton Rouge, Louisiana, United StatesActive Not Recruiting
Our lady of the Lake HospitalBaton Rouge, Louisiana, United StatesActive Not Recruiting

+ 37 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05431088