EichorEICHOR
Study identifier: NCT05422222 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

Condition: Cystic Fibrosis  ·  Sponsor: Vertex Pharmaceuticals Incorporated

PhasePhase 3
Planned participants210
Who can joinAll sexes, 1 Year to 11 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at least 1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (38)

Children's Hospital of Orange CountyOrange, California, United States
Stanford University Clinical and Translational Research UnitPalo Alto, California, United States
Children's Hospital of ColoradoAurora, Colorado, United States
The Emory Clinic / Children's Healthcare of Atlanta at EglestonAtlanta, Georgia, United States
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United States
Riley Hospital for Children at Indiana University HealthIndianapolis, Indiana, United States
Boston Children's HospitalBoston, Massachusetts, United States
Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of MinnesotaMinneapolis, Minnesota, United States
The Children's Mercy HospitalKansas City, Missouri, United States
Washington University School of Medicine / St. Louis Children's HospitalSt Louis, Missouri, United States
Cohen Children's Medical CenterLake Success, New York, United States
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United States

+ 26 more locations — full list on the registry record.

Follow this study

Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.

We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →