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Improve New Learning and Memory in Individuals With Mild Cognitive Impairment
Condition: Mild Cognitive Impairment · Sponsor: Kessler Foundation
About this study
The current study is a double-blind, placebo-control randomized clinical trial examining the efficacy of memory retraining in individuals with Mild Cognitive Impairment (MCI). Impairment in higher level cognitive processing, such as new learning and memory, is one of the most common deficits in individuals with MCI and such deficits have been shown to exert significant negative impact on multiple aspects of everyday life, including occupational and social functioning. Despite these findings, few studies have attempted to treat these cognitive deficits in order to improve the everyday functioning of individuals with MCI. Through a small randomized clinical trial, the investigators found that individuals with MCI with documented cognitive impairment show a significant improvement in their memory performance following a treatment protocol designed to facilitate learning. The current proposal will replicate this finding and further evaluate (a) the impact of the treatment on everyday functioning, (b) the long term efficacy of the treatment and (c) the utility of booster sessions in facilitating long-term treatment effects. We will randomly assign older individuals who meet criteria for a diagnosis of amnestic MCI to a memory retraining group or a placebo control group. Both groups will undergo baseline, immediate and long-term follow-up assessment consisting of: (1) a traditional neuropsychological battery, (2) an assessment of global functioning examining the impact of the treat…
This description comes directly from the study's public registry record.
Talk to the study team
Nancy Moore · 1973-324-8450 · nbmoore@kesslerfoundation.org
Nancy Chiaravalloti · 973-324-8440 · nchiaravalloti@kesslerfoundation.org
Always discuss trial participation with your own doctor first.
Locations (2)
| University of Michigan | Ann Arbor, Michigan, United States | Recruiting |
| Kessler Foundation Research Center | West Orange, New Jersey, United States | Recruiting |
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