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Study identifier: NCT05388708 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)

Condition: Acute Respiratory Distress Syndrome · Extracorporeal Membrane Oxygenation  ·  Sponsor: University of Michigan

PhaseN/A
Planned participants550
Who can joinAll sexes, 14 Days to 20 Years
Healthy volunteersNo

About this study

ASCEND researchers are partnering with families of children who receive extracorporeal membrane oxygenation (ECMO) after a sudden failure of breathing named pediatric acute respiratory distress syndrome (PARDS). ECMO is a life support technology that uses an artificial lung outside of the body to do the lung's work. ASCEND has two objectives. The first objective is to learn more about children's abilities and quality of life among ECMO-supported children in the year after they leave the pediatric intensive care unit. The second objective is to compare short and long-term patient outcomes in two groups of children: one group managed with a mechanical ventilation protocol that reserves the use of extracorporeal membrane oxygenation (ECMO) until protocol failure to another group supported on ECMO per usual care.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (95)

Children's of AlabamaBirmingham, Alabama, United States
Phoenix Children's HospitalPhoenix, Arizona, United States
Arkansas Children's HospitalLittle Rock, Arkansas, United States
Loma Linda University Children's HospitalLoma Linda, California, United States
UCLA Mattel Children's HospitalLos Angeles, California, United States
Valley Children's HospitalMadera, California, United States
UCSF Benioff Children's Hospital OaklandOakland, California, United States
Children's Hospital of Orange CountyOrange, California, United States
Lucile Packard Children's Hospital StanfordPalo Alto, California, United States
UCSF Benioff Children's Hospital - San FranciscoSan Francisco, California, United States
Children's Hospital ColoradoAurora, Colorado, United States
Connecticut Children's Medical CenterHartford, Connecticut, United States

+ 83 more locations — full list on the registry record.

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