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Study identifier: NCT05388669 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Condition: Advanced or Metastatic Non-small Cell Lung Cancer  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants418
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of the study is to simplify amivantamab intravenous administration and to reduce dose times, by assessing a new formulation of amivantamab, amivantamab subcutaneous and co-formulated with recombinant human hyaluronidase (SC-CF), for subcutaneous administration. This formulation has the potential to enhance both the patient and physician experience with amivantamab by providing easier and accelerated administration.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (187)

City of Hope DuarteDuarte, California, United States
City of Hope Orange County Lennar Foundation Cancer CenterIrvine, California, United States
City of Hope Long Beach ElmLong Beach, California, United States
National Jewish HealthDenver, Colorado, United States
Baptist Lynn Cancer InstituteBoca Raton, Florida, United States
Orlando HealthOrlando, Florida, United States
University of KansasKansas City, Kansas, United States
University of MichiganAnn Arbor, Michigan, United States
Astera Cancer CareEast Brunswick, New Jersey, United States
Rutgers Cancer Institute of New JerseyNew Brunswick, New Jersey, United States
NYU Langone Health Laura and Isaac Perlmutter Cancer CenterNew York, New York, United States
Montefiore Medical CenterThe Bronx, New York, United States

+ 175 more locations — full list on the registry record.

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